nutlin 3


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102 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 E3 ubiquitin-protein ligase Mdm2 - MDM2 Camelus bactrianus 105081337 1 1
2 PDGF- and VEGF-related factor 1 Q9BLX1_DROME Pvf1 Drosophila melanogaster 32876 11 1
3 BCL2 associated X, apoptosis regulator BAX_HUMAN BAX Homo sapiens 581 3031 1
4 sirtuin 1 SIR1_HUMAN SIRT1 Homo sapiens 23411 1253 1
5 protein kinase, DNA-activated, catalytic subunit PRKDC_HUMAN PRKDC Homo sapiens 5591 418 1
6 DEK proto-oncogene DEK_HUMAN DEK Homo sapiens 7913 67 1
7 SKI proto-oncogene SKI_HUMAN SKI Homo sapiens 6497 126 1
8 mitogen-activated protein kinase 3 MK03_HUMAN MAPK3 Homo sapiens 5595 3238 2
9 H3 histone pseudogene 16 - H3P16 Homo sapiens 644914 2095 7
10 E2F transcription factor 1 E2F1_HUMAN E2F1 Homo sapiens 1869 403 3
11 high mobility group AT-hook 2 HMGA2_HUMAN HMGA2 Homo sapiens 8091 179 1
12 mitogen-activated protein kinase kinase 7 MP2K7_HUMAN MAP2K7 Homo sapiens 5609 1407 1
13 caspase 3 CASP3_HUMAN CASP3 Homo sapiens 836 5209 4
14 catenin beta 1 CTNB1_HUMAN CTNNB1 Homo sapiens 1499 2350 1
15 phosphatase and tensin homolog PTEN_HUMAN PTEN Homo sapiens 5728 1316 2
16 poly(ADP-ribose) polymerase 1 PARP1_HUMAN PARP1 Homo sapiens 142 2571 1
17 MDM2 proto-oncogene MDM2_HUMAN MDM2 Homo sapiens 4193 873 99
18 tumor protein p73 P73_HUMAN TP73 Homo sapiens 7161 217 5
19 MYCN proto-oncogene, bHLH transcription factor MYCN_HUMAN MYCN Homo sapiens 4613 374 3
20 ATP binding cassette subfamily B member 1 MDR1_HUMAN ABCB1 Homo sapiens 5243 3985 1
21 RAD51 recombinase RAD51_HUMAN RAD51 Homo sapiens 5888 537 1
22 DNA damage inducible transcript 3 DDIT3_HUMAN DDIT3 Homo sapiens 1649 1082 1
23 suppressor of cytokine signaling 1 SOCS1_HUMAN SOCS1 Homo sapiens 8651 658 1
24 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 106
25 latexin LXN_HUMAN LXN Homo sapiens 56925 5329 1
26 protein phosphatase, Mg2+/Mn2+ dependent 1D PPM1D_HUMAN PPM1D Homo sapiens 8493 77 3
27 proopiomelanocortin COLI_HUMAN POMC Homo sapiens 5443 2059 1
28 BCL2 related protein A1 B2LA1_HUMAN BCL2A1 Homo sapiens 597 491 1
29 cyclin dependent kinase 9 CDK9_HUMAN CDK9 Homo sapiens 1025 239 2
30 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 1
31 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 3
32 cyclin D1 CCND1_HUMAN CCND1 Homo sapiens 595 1747 1
33 ABL proto-oncogene 1, non-receptor tyrosine kinase ABL1_HUMAN ABL1 Homo sapiens 25 989 1
34 cyclin dependent kinase inhibitor 2A ARF_HUMAN CDKN2A Homo sapiens 1029 859 1
35 mitogen-activated protein kinase 1 MK01_HUMAN MAPK1 Homo sapiens 5594 4181 1
36 RUNX family transcription factor 2 RUNX2_HUMAN RUNX2 Homo sapiens 860 661 2
37 glutathione S-transferase pi 1 GSTP1_HUMAN GSTP1 Homo sapiens 2950 703 1
38 RB transcriptional corepressor 1 RB_HUMAN RB1 Homo sapiens 5925 809 1
39 BCL2 like 1 B2CL1_HUMAN BCL2L1 Homo sapiens 598 1360 2
40 annexin A5 ANXA5_HUMAN ANXA5 Homo sapiens 308 1785 1
41 nucleophosmin 1 NPM_HUMAN NPM1 Homo sapiens 4869 371 1
42 potassium voltage-gated channel subfamily H member 1 KCNH1_HUMAN KCNH1 Homo sapiens 3756 137 1
43 protein phosphatase 1 regulatory subunit 13 like IASPP_HUMAN PPP1R13L Homo sapiens 10848 37 1
44 utrophin UTRN_HUMAN UTRN Homo sapiens 7402 137 1
45 ribonuclease P/MRP subunit p14 RPP14_HUMAN RPP14 Homo sapiens 11102 106 1
46 MCL1 apoptosis regulator, BCL2 family member MCL1_HUMAN MCL1 Homo sapiens 4170 1015 1
47 TNF superfamily member 10 TNF10_HUMAN TNFSF10 Homo sapiens 8743 1439 3
48 WT1 transcription factor WT1_HUMAN WT1 Homo sapiens 7490 267 1
49 BCL2 antagonist/killer 1 BAK_HUMAN BAK1 Homo sapiens 578 490 1
50 ATM serine/threonine kinase ATM_HUMAN ATM Homo sapiens 472 847 1